1-(4-chlorophenyl)cyclopropanecarboxylic acid

1-(4-chlorophenyl)cyclopropanecarboxylic acid - Names and Identifiers

Name	1-(4-Chlorophenyl)-1-cyclopropanecarboxylic acid
Synonyms	RARECHEM AL BO 1115 TIMTEC-BB SBB003583 1-(4-chlorophenyl)cyclopropanecarboxylate 1-(p-Chlorophenyl)cyclopropanecarboxylic acid 1-(4-chlorophenyl)cyclopropanecarboxylic acid 1-(4-CHLOROPHENYL)CYCLOPROPANECARBOXYLIC ACID 1-(p-Dhlorophenyl)cyclopropanecarboxylic acid. 1-(4-CHLOROPHENYL)-1-CYCLOPROPANECARBOXYLIC ACID cyclopropanecarboxylic acid, 1-(4-chlorophenyl)- 1-(4-Chlorophenyl)-1-cyclopropanecarboxylic acid
CAS	72934-37-3
EINECS	277-105-5
InChI	InChI=1/C10H9ClO2/c11-8-3-1-7(2-4-8)10(5-6-10)9(12)13/h1-4H,5-6H2,(H,12,13)/p-1

1-(4-chlorophenyl)cyclopropanecarboxylic acid - Physico-chemical Properties

Molecular Formula	C10H9ClO2
Molar Mass	196.63
Density	1.2040 (rough estimate)
Melting Point	152-155 °C
Boling Point	152-155°C
Flash Point	157.4°C
Solubility	soluble in Methanol
Vapor Presure	4.33E-05mmHg at 25°C
Appearance	Crystalline Powder
Color	White
pKa	4.14±0.20(Predicted)
Storage Condition	Inert atmosphere,Room Temperature
Refractive Index	1.5152 (estimate)
MDL	MFCD00001289

1-(4-chlorophenyl)cyclopropanecarboxylic acid - Risk and Safety

Risk Codes	R36/37/38 - Irritating to eyes, respiratory system and skin. R20/22 - Harmful by inhalation and if swallowed. R41 - Risk of serious damage to eyes
Safety Description	S37/39 - Wear suitable gloves and eye/face protection S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
HS Code	29163900
Hazard Class	IRRITANT

1-(4-chlorophenyl)cyclopropanecarboxylic acid - Introduction

1-(4-Chlorophenyl)-1-cycloprocecarboxylic acid is an organic compound with a molecular formula of C10H9ClO2 and a relative molecular mass of 196.63g/mol. It is a white or off-white solid, soluble in organic solvents such as alcohols and esters.

This compound is mainly used in the pharmaceutical field, as an intermediate and raw material for some drugs. It can be used as an important starting material or intermediate for the synthesis of other organic compounds.

The preparation method of 1-(4-Chlorophenyl)-1-cyclopropanecarboxylic acid can be achieved by cyclopropane ring opening reaction and substitution reaction. The specific steps include reacting 1,1-dichlorocyclopropane with 4-chlorobenzyl alcohol under alkali catalysis to generate 1-(4-chlorophenyl) cyclopropane, which is then subjected to oxidation and hydroxymethylation to obtain the target product.

Certain safety precautions need to be observed when using or handling 1-(4-Chlorophenyl)-1-cyclopropanecarboxylic acid. It may be irritating to the eyes, skin and respiratory system, so contact should be avoided. Appropriate protective equipment such as gloves, goggles and protective clothing should be used during handling. At the same time, it should be operated in a well-ventilated place to avoid inhaling gas or vapor. If unwell caused by accidental contact or inhalation, seek medical attention immediately.

Last Update：2024-04-09 21:11:58